My name is Janice Pang, and I’m currently in grade 9. In school, I actively take part in the grade 9 advisory council and is a member of the volleyball team. Outside of school, I enjoy going curling and competing in the Optimist Junior Curling League. Previously, I have participated in the 2012 Canada-Wide Science Fair. This year microbiology continues to be an interest of mine. To have the opportunity to continue conducting experiments in a research lab was amazing.
The passion I had for learning about the pathogenesis of type 2 diabetes had inspired me to do this project. In the future, I hope to continue researching about type 2 diabetes. As well, if students are thinking about doing a project, starting early will be the key to success.
Pancreatic islets were treated with IAPP to identify whether IAPP activates caspase-1 in pancreatic islets. The effects of islet macrophages on insulin secretion and production was also investigated. This study provides a better understanding of the pathogenesis of type 2 diabetes and suggest a therapeutic treatment in which the stimulus of inflammation can be targeted, to improve insulin secretion and beta cell function.
Winner of the Excellence Award - Gold Medal (Intermediate) at the Canada Wide Science Fair 2013